In The News
HVAC & Environmental Control for Pharma Manufacturing Facilities
Genesis AEC’s President, Norm Goldschmidt, shares his Heating, Ventilation, and Air Conditioning (HVAC) system insights with Pharmaceutical Engineering magazine.
What are the top three challenges for HVAC systems in pharmaceutical manufacturing facilities?
Originally published by ISPE’s iSpeak Blog.
- HVAC: Heating, Ventilation, and Air Conditioning – A system used for regulating the ambient environmental conditions in a facility.
- Clean Room: A room with controlled environmental parameters such as humidity, temperature, and particulate contamination, often used in pharmaceutical manufacturing.
- Air-Change Rate: The frequency at which the air in a specific area is replaced by fresh air, often measured in changes per hour.
- HEPA Filter: High Efficiency Particulate Air Filter – A filter that is designed to capture particulates in the air.
- Pore Size: A misnomer often used to describe the filter openings in HEPA filters, although not technically applicable.
- Aerosols: A suspension of fine solid particles or liquid droplets in air or another gas.
- Viable/Non-Viable Particles: Viable particles are capable of growing (e.g., bacteria, viruses), whereas non-viable particles are not (e.g., dust, pollen).
- Process: Refers to the series of actions or steps taken in manufacturing or other production activities.
- Qualification: The act of proving that a system, process, or equipment performs as expected under given conditions.
- Schematic Engineering: Engineering drawings that represent the elements of a system using abstract, graphic symbols rather than realistic pictures.
- Verification Testing: A testing process that is used to evaluate if a system is meeting specified requirements.
- Preventive/Predictive Maintenance: Maintenance strategies aimed at preventing or predicting future system failures.
- Sustainability: The ability to meet the needs of the present without compromising the ability of future generations to meet their own needs.
- Primary/Secondary System Configuration: A more efficient HVAC system setup that conditions outside air and recirculates return air through separate systems.
- Automated Disinfection/Decontamination: Use of automated systems to sterilize or clean an environment, which may involve sporicides and other disinfectants.
- Adaptive Control: Control systems that adjust in real-time based on changing conditions.
- ISPE’s iSpeak Blog: A blog from the International Society for Pharmaceutical Engineering, which provides professional opinions, reviews, and articles related to the pharmaceutical industry.